The clusters included in the South Carolina grouping are:
- Aiken Area (M1)
- Chester-Fairfield-York (M2)
- Greater Augusta Area GA (M1)
- Greater Columbia Area (M2)
- Greenville (M2)
- Greenwood Area (M1)
- Kershaw-Lancaster (M1)
- Laurens-Newberry (M1)
- Spartanburg (M2)
- Upstate Foothills (M2)